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Docking Success Rate Comparison

Success Rate (% of poses within 2 Å RMSD)

Boltz-2 ★
~84%
AlphaFold 3
73–76%
DO Dock
69%
DOCK 6 ★
~35–45%
AutoDock Vina ★
~30–40%
Chai-2 ★
?  No published ≤ 2 Å metric
25%
50%
75%
100%
Evaluated on PoseBusters benchmark
Alternative / dataset-specific benchmark ★

★ Results not evaluated on the PoseBusters benchmark. Reported values are drawn from dataset-specific or alternative docking benchmarks and are not directly comparable to PoseBusters ≤ 2 Å RMSD success rates.